Antonella Forlino Selected Research

Collagen Type I (Type I Collagen)

1/2022	Dissecting the phenotypic variability of osteogenesis imperfecta.
1/2022	Compression Fractures and Partial Phenotype Rescue With a Low Phosphorus Diet in the Chihuahua Zebrafish Osteogenesis Imperfecta Model.
6/2021	The Stimulating Effect of Rosmarinic Acid and Extracts from Rosemary and Lemon Balm on Collagen Type I Biosynthesis in Osteogenesis Imperfecta Type I Skin Fibroblasts.
1/2021	Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta.
5/2020	Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing.
1/2020	Substitution of murine type I collagen A1 3-hydroxylation site alters matrix structure but does not recapitulate osteogenesis imperfecta bone dysplasia.
12/2018	Early Fracture Healing is Delayed in the Col1a2+/G610C Osteogenesis Imperfecta Murine Model.
5/2018	4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion.
1/2018	Severely Impaired Bone Material Quality in Chihuahua Zebrafish Resembles Classical Dominant Human Osteogenesis Imperfecta.
8/2017	Osteogenesis imperfecta.

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Antonella Forlino Research Topics

Disease

22	Osteogenesis Imperfecta (Lobstein Disease) 01/2022 - 05/2004
11	Prolidase Deficiency 01/2020 - 10/2002
7	Diastrophic dysplasia 01/2021 - 03/2005
5	Congenital Abnormalities (Deformity) 01/2022 - 07/2010
4	Developmental Bone Diseases (Bone Dysplasia) 01/2020 - 07/2012
3	Intellectual Disability (Idiocy) 05/2010 - 10/2002
2	Breast Neoplasms (Breast Cancer) 12/2021 - 01/2008
2	Desbuquois syndrome 08/2021 - 01/2019
2	Bone Diseases (Bone Disease) 01/2019 - 01/2017
2	Neoplasms (Cancer) 03/2014 - 12/2013
2	Carcinogenesis 01/2013 - 01/2008
1	Compression Fractures (Compression Fracture) 01/2022
1	Inflammation (Inflammations) 01/2022
1	Body Weight (Weight, Body) 01/2021
1	Skin Ulcer 01/2020
1	Rare Diseases (Rare Disease) 01/2020
1	Wounds and Injuries (Trauma) 01/2017
1	Ulcer 03/2016
1	Primary Immunodeficiency Diseases 07/2015
1	Microcephaly 03/2015
1	Genu Valgum 03/2015
1	Metabolic Bone Diseases (Osteopenia) 03/2015
1	Hypertelorism 03/2015
1	Stroke (Strokes) 02/2015
1	Adenoma (Adenomas) 03/2014
1	Hyperplasia 03/2014
1	Cushing Syndrome 03/2014
1	Shock 01/2013
1	Omani type Spondyloepiphyseal dysplasia 08/2012
1	Platybasia (Basilar Impression) 09/2010
1	Respiratory Tract Infections (Respiratory Tract Infection) 05/2010
1	Connective Tissue Diseases (Connective Tissue Disease) 07/2008
1	Carcinoma (Carcinomatosis) 01/2008
1	Inborn Genetic Diseases (Disease, Hereditary) 06/2007
1	Ichthyosis (Xeroderma) 05/2007
1	Laminopathies 05/2007

Drug/Important Bio-Agent (IBA)

19	Collagen Type I (Type I Collagen)IBA 01/2022 - 05/2004
14	proline dipeptidase (prolidase)IBA 01/2022 - 10/2002
14	CollagenIBA 12/2021 - 05/2004
11	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2007
5	Sulfates (Sulfates, Inorganic)IBA 01/2021 - 09/2006
3	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2021 - 07/2009
3	alpha2 Subunit Collagen Type IIBA 05/2020 - 08/2017
3	Proteoglycans (Proteoglycan)IBA 07/2010 - 03/2007
3	Sulfate TransportersIBA 07/2010 - 03/2005
2	Acetylcysteine (Siran)FDA LinkGeneric 01/2021 - 10/2015
2	ChloridesIBA 01/2021 - 10/2015
2	EnzymesIBA 09/2011 - 10/2002
2	Diphosphonates (Bisphosphonates)IBA 06/2011 - 09/2010
2	IntegrinsIBA 07/2008 - 03/2007
2	DipeptidesIBA 06/2005 - 09/2003
1	MineralsIBA 01/2022
1	Phosphorus (Red Phosphorus)IBA 01/2022
1	Estrogen ReceptorsIBA 12/2021
1	Proline Oxidase (Proline Dehydrogenase)IBA 12/2021
1	Proline (L-Proline)FDA Link 12/2021
1	Estrogens (Estrogen)FDA Link 12/2021
1	Tumor Viral Antigens (Large T Antigen)IBA 08/2021
1	GlycosaminoglycansIBA 08/2021
1	Rosmarinic AcidIBA 06/2021
1	2-oxoglutarate 3-dioxygenase prolineIBA 01/2020
1	CalciumIBA 01/2019
1	Uridine Diphosphate (UDP)IBA 01/2019
1	cyclophilin BIBA 01/2019
1	nucleotidaseIBA 01/2019
1	4-phenylbutylamineIBA 05/2018
1	Alcian BlueIBA 01/2017
1	alizarinIBA 01/2017
1	fluorexon (calcein)IBA 01/2017
1	ursodoxicoltaurineIBA 01/2017
1	Sulfhydryl Compounds (Thiols)IBA 10/2015
1	AntiportersIBA 10/2015
1	dipeptidaseIBA 07/2015
1	Mutant Proteins (Protein, Mutant)IBA 03/2015
1	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2014
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 03/2014
1	Adrenocorticotropic Hormone (ACTH)FDA Link 03/2014
1	Pharmaceutical PreparationsIBA 12/2013
1	Sodium-Hydrogen ExchangersIBA 12/2013
1	MetalsIBA 01/2013
1	CarbohydratesIBA 08/2012
1	SulfotransferasesIBA 08/2012
1	ChondroitinIBA 08/2012
1	Human Growth Hormone (Saizen)FDA LinkGeneric 06/2011
1	HSP47 Heat-Shock Proteins (Heat Shock Protein 47)IBA 06/2011
1	Procollagen Type IIBA 06/2011
1	Growth Hormone (Somatotropin)IBA 09/2010
1	Chondroitin Sulfate ProteoglycansIBA 07/2010
1	Growth InhibitorsIBA 01/2008
1	DecorinIBA 01/2008
1	Biomarkers (Surrogate Marker)IBA 01/2008
1	Lamin B ReceptorIBA 05/2007
1	SterolsIBA 05/2007
1	CholesterolIBA 05/2007

Therapy/Procedure

5	Therapeutics 01/2022 - 07/2009
1	Injections 01/2021
1	Hematopoietic Stem Cell Transplantation 01/2012
1	Operative Surgical Procedures 06/2011
1	Physical Therapy Modalities (Physical Therapy Technique) 09/2010
1	Transplantation 07/2009